Full-spectrum CBD, for example, usually contains additional cannabinoids, terpenes, and possibly even trace levels of THC (the psychoactive compound in marijuana). On the other hand, CBD isolate contains nothing else, making it best suited for people who want to consume only CBD.
After meticulously reviewing more than 100 top CBD brands in search of the most reliable options, we've identified the 5 best CBD isolate products on the market. These high-quality picks-which come as powders, capsules, gummies, and more-have been selected based on customer reviews, price, lab testing, and hemp sourcing.
How is CBD isolate made?
When hemp oil is first extracted from the cannabis plant, it contains a variety of cannabinoids, terpenes, and other botanical compounds. This hemp oil can be put through further chemical processes to refine it, separate all those "extra" ingredients, and yield something that's pure CBD, resulting in CBD isolate. To get more specific, CBD isolate is formulated with at least 95% CBD, although most isolate products have closer to 99% CBD content.
These are the 5 best CBD isolate products on the market right now:
If you prefer your isolate in a powder form, CBDistillery is a top choice. This THC-free product is carefully tested via third-party labs, and the test results are easily found within the product description and imagery. It’s also very easy to incorporate into food or drink, offering a simplicity of use that few CBD products can match. With 970 milligrams of CBD per gram, this isolate powder is sourced from U.S.-grown hemp that’s non-GMO and made with natural farming practices.
Interestingly, two different teams identified CBC during the same year, using two different methods. Mechoulam and Gaoni isolated and identified the structure of CBC in 1966. Starting out with a hexane extract, the two researchers ran a chromatography test and identified CBD, THC, CBN, CBG, and CBC. Cannabichromene made up around 1.5% of the extract.
CBC (cannabichromene) makes up around 0.3% of cannabis plant extract. However, breeders have developed cultivars expressing significantly higher amounts. A non-psychoactive cannabinoid, researchers have explored the pharmacological actions of CBC, finding some intriguing potential.
THC produces most of the psychoactive effects associated with cannabis. This controversial molecule attaches to the CB1 receptor of the endocannabinoid system to produce these outcomes. Shortly after discovering CBG, Mechoulam and Gaoni cracked the code and identified and isolated THC (delta-9-tetrahydrocannabinol).
• CBC (1966)
In the hunt for alkaloids, Klein and colleagues isolated cannabimines A, B, C, and D. Shortly after, researchers isolated the alkaloids cannabisativine, from the roots of a Mexican landrace, and anhydrocannabisativine, from the roots and leaves of another wild Mexican strain.
Scientists were on the trail of a new compound, but they couldn’t quite figure out what was generating these effects. Many argued cannabis housed alkaloids, with Preobrajensky claiming the plant to possess nicotine.
In 1840, a researcher by the name of Schlesinger reportedly obtained the first active extract from the flowers and leaves of hemp plants. Shortly after, another experimental mind named Decourtive conducted an ethanol extract of similar materials in 1848. He evaporated the alcohol and found a dark resin in its place. He named the substance “cannabin”.
United States chemist Roger Adams first isolated CBD (cannabidiol) from cannabis in 1942. He extracted the now world-famous cannabinoid from the flowers of Minnesota wild hemp. Adams conducted an ethanol extraction to create a “red oil”. He then ran the substance through distillation under diminished pressure and isolated cannabidiol from the mix of constituents.