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So which is the best? The method of cannabis consumption that suits your current needs.

Edibles tend to have the greatest variance in effects on the largest amount of cannabis users. Sometimes the high can be all waiting. A negligible high eventually hits you and moves on before too long. Other times it can creep up on you. A couple of hours after you scoffed a fistful of brownies and wham! You’re completely couchlocked.

Smoking and vaping are the most popular methods of cannabis consumption for recreational users. Inhaling cannabinoids directly through the lungs is efficient and increases bioavailability to 50% or above. The effects are felt rapidly, usually within tokes. The THC high can also last for an hour or more if your stash is potent bud.

HOMEMADE HIGH THC EDIBLES

Oral administration of CBD involves a very different metabolic pathway than that of smoked or sublingually administered cannabinoids. The latter enter the bloodstream instantly and produce almost immediate effects with a shorter duration. Oral CBD must first pass through the GI tract and then through the liver. This longer route to the blood-brain barrier means the effects take longer to set in, but the duration of effects is longer.

Tinctures and space cakes are back! That’s right gobbling ganja is on the rise. It’s time we took a closer look at the effects of two trending alternatives to smoking. Sub-lingual and oral ingestion are common consumption methods for both recreational and medicinal cannabis users. Keeping reading to find out why.

Oral ingestion of cannabis, on the other hand, does not offer quick results. What it does offer are longer, often stronger highs. As the cannabinoids become available at a slower rate, and the THC is converted into a more psychoactive form, it can feel like a much punchier, stronger experience. The problem with it is that it can be hard to dose evenly between portions.

Despite the 100mg/THC limitations per pack and 10mg/THC per serving on edibles in California, the homemade space cake renaissance is well underway here in Europe. Cannabis cuisine and dank desserts are seeing a resurgence in popularity. Old favourites like cannabis-infused brownies and decadent space cakes are safe to consume inconspicuously at social events and gatherings. A pinch of cannabis-infused curry or other sauce may be offered up for dinner at the right kind of reefer party.

Once there, it has to stay in circulation long enough to be delivered to the organs and tissues where it is needed.

Oral CBD formulations, such as liquid drops, capsules, tinctures, foods, and beverages are among the most popular ways to consume CBD. But oral CBD has the lowest bioavailability of all delivery forms.

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Oral CBD has also been found to lead to higher brain levels when compared to inhalation methods in animal studies [6].

CBD offers great potential for health and healing. Its high safety profile and non-addictive nature make it an appealing alternative to many conventional drugs.

Not all CBD is the same. Discover the differences between CBD delivery forms and the pros and cons of each. Learn how to choose the best CBD form for you.

Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in inflammatory bowel disease (IBD) patients. Here, we have investigated the effect of a standardized Cannabis sativa extract with high content of cannabidiol (CBD), here named CBD BDS for “CBD botanical drug substance,” on mucosal inflammation and hypermotility in mouse models of intestinal inflammation. Colitis was induced in mice by intracolonic administration of dinitrobenzenesulfonic acid (DNBS). Motility was evaluated in the experimental model of intestinal hypermotility induced by irritant croton oil. CBD BDS or pure CBD were given – either intraperitoneally or by oral gavage – after the inflammatory insult (curative protocol). The amounts of CBD in the colon, brain, and liver after the oral treatments were measured by high-performance liquid chromatography coupled to ion trap-time of flight mass spectrometry. CBD BDS, both when given intraperitoneally and by oral gavage, decreased the extent of the damage (as revealed by the decrease in the colon weight/length ratio and myeloperoxidase activity) in the DNBS model of colitis. It also reduced intestinal hypermotility (at doses lower than those required to affect transit in healthy mice) in the croton oil model of intestinal hypermotility. Under the same experimental conditions, pure CBD did not ameliorate colitis while it normalized croton oil-induced hypermotility when given intraperitoneally (in a dose-related fashion) or orally (only at one dose). In conclusion, CBD BDS, given after the inflammatory insult, attenuates injury and motility in intestinal models of inflammation. These findings sustain the rationale of combining CBD with other minor Cannabis constituents and support the clinical development of CBD BDS for IBD treatment.

Keywords: Cannabis sativa; cannabidiol; cannabinoids; colitis; inflammatory bowel disease; intestinal motility.