“The type of food can make a large difference in the amount of CBD that gets absorbed into the body. Although fatty foods can increase the absorption of CBD, it can also increase the variability as not all meals contain the same amount of fat,” said Angela Birnbaum, Ph.D., a professor in the College of Pharmacy and study co-author, in a press release.
The small study included eight adults who were prescribed CBD for seizures related to epilepsy (a condition which CBD has been FDA-approved for). For the first part of the study, half the volunteers took their CBD first thing in the morning before eating and had breakfast four hours later, while the other half ate a high-fat breakfast burrito, containing about 850 calories and 52 percent fat, within 30 minutes of taking their CBD oil. After two weeks, they switched groups.
Now, research published in the journal Epilepsia shows that the food you eat along with your CBD supplement may have a dramatic effect on how much of the compound your body absorbs—and that may play a role in how effective it is.
Cannabidiol (CBD) oil has become a multi-billion dollar industry, with recreational athletes dishing out a large chunk of that change for the promise of pain relief, faster recovery, better sleep, and more.
The researchers concluded that CBD should be taken with food to maximize absorption, and that a low-fat meal may not have the same absorption boosting effect as one that is higher in fat.
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Some people claim remarkable benefits from CBD, while others find effects elusive at best. Myriad factors influence how well (or not) you respond to CBD, including the type you take, how much you take, and even your genes.
“I thought I was in the clear,” J.C. says. “From everything that I had heard, CBD oil wasn’t supposed to show up on drug tests.”
Plus, he says, in some cases that percentage is based on the weight of the whole plant, or on the weight of the buds or flowers, which tend to have more THC.
Not always, even though it’s legal. Here’s how to protect yourself.
But as more people try it, one unexpected “side effect” could be failing an employer’s drug test, and even losing a job as a result.
Best bet: To increase the likelihood that a product doesn’t have more THC than claimed, look for a manufacturer that can provide a Certificate of Analysis, or COA, for its product. That document shows the results of a company’s testing for THC, CBD, and various contaminants. Though that testing is voluntary (except in Indiana and Utah) and the results aren’t confirmed by independent experts, for now it’s the best information available. If a store or website can’t provide you with a COA, look for another product. Read more about how CBD products are tested.
And he believes those high levels could be due in part to how THC levels are measured in hemp plants. While those plants are supposed to contain no more than 0.3 percent THC, that’s based on the dry weight of the plant. “But dry weight doesn’t necessarily equate to what’s in the finished product,” Sample says.