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sample cbd tincture kis

BOD Australia Pty Ltd, Sydney, Australia

Dr Adele Hosseini, BOD Australia Pty Ltd, Sydney, Australia.

Methods

This study investigated the safety, tolerability and pharmacokinetics after administration of a specific Cannabis sativa cultivar extract, standardised to cannabidiol (CBD) content as sublingual wafer or oil formulation compared to nabiximols oromucosal spray.

The extract was generally well tolerated by participants when administered in either wafer or oil form, with some adverse events, including mild or moderate somnolence, sedation and altered mood. The relative bioavailability of CBD after administration as a sublingual wafer was comparable with that of oil solution with 90% confidence interval of 83–131%. The median maximum concentrations of CBD after administration of oil solution and wafer was 9.4 and 11.9 ng mL −1 , respectively. Maximum concentrations of CBD occurred 4 hours after administration, with an estimated terminal elimination half-life of 6 hours. There was no statistically significant difference between the AUC0-τ of CBD after administration of oil solution or wafer compared with nabiximols oromucosal spray.

Nucleus Network Pty Ltd, Melbourne, Australia

Similarly, CBD oil — an acronym for cannabidiol derived from the cannabis plant — that surfaced in the NCB’s investigation of WhatsApp chats between Sushant Singh Rajput’s talent manager Jaya Saha and Rhea Chakraborty, Saha’s lawyer said, would not come under the NDPS Act.

As potent as various parts of its anatomy may be, not all of them amount to criminality under the Narcotic Drugs and Psychotropic Substances (NDPS) Act, 1985.

Former head of the psychiatry department at AIIMS, Dr Sudhir Khandewal said, “Some states in the US have legalised CBD oil but we do not prescribe it here. Cannabis content is very low and it has very low THC and has no addictive properties. More than anxiety and depression, it has been found useful in cancer treatment like in multiple myeloma. For associated symptoms of cancer it has been found useful. There have been several discussions on this. Cannabis is mired in so much controversy. It should not have been in the NDPS Act, but unfortunately, it is.”

How does the NDPS Act define cannabis?

According to the NDPS Act “cannabis plant” means any plant of the genus cannabis. The legislation that was enacted in 1985 succeeded the Dangerous Drugs Act, 1930. It was introduced as lawmakers felt that the older legislation that entailed a maximum punishment of up to four years was not strict enough to check drug trafficking.

Bollywood actress Rhea Chakraborty leaves in her car after she was granted bail by Bombay High Court in a drug case linked to late actor Sushant Singh Rajput’s death, in Mumbai, Wednesday, Oct. 7, 2020. (PTI Photo: Mitesh Bhuvad)

“Our research shows that CBD oil is made from the leaves of the cannabis plant and hence does not attract the NDPS Act,” said criminal lawyer Ayaz Khan, who represents Saha. The information on the bottle of the ‘CiBiDiUM’ brand of the oil that Saha suggested Rhea could give Rajput, stated that it contained no THC.

Under section 2 (iii), the Act defines cannabis (hemp). The sub-sections refer to parts of the plant that come under the purview of the Act.

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