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JY: I work in the liquid chromatography applications department at Restek. I have a very diverse job and it keeps things exciting. I spend time developing chromatographic methods, processing data, conducting technical support, developing sample preparation methods, supporting new product development, and researching trending topics across multiple markets.

JY: Of course, one of the most important things in chromatographic analysis is the column. For this workflow, I used a Raptor ARC-18 column. This column is robust and perfect for high-throughput applications. The column was equipped with a Raptor ARC-18 guard cartridge to help protect the analytical column and improve column lifetime. It’s also important to note that Raptor ARC-18 is quality tested specifically for the analysis of cannabinoids to ensure consistent lot-to-lot performance. Additionally, filter vials are absolutely critical in cannabinoid analysis workflows. Filtration prior to injection removes particulates present in the sample that could potentially clog your column.

Can you tell us more about your job role and what you do on a daily basis?

Creams, lotions, and balms can be really tricky samples. I think it’s a great tool when first starting a new project to see what’s been previously done. There’s no need to reinvent the wheel. We have an application note published on the Restek website on CBD lotions, balms, and creams, so it’s a great place to start if that’s something a lab is looking to add to their workflow. It’s important when first addressing a challenging matrix to not box yourself in. Make sure to set yourself up for future success by doing a thorough job with the initial method development. Time spent upfront will pay dividends in the end. If any questions arise, Restek is always here to help so don’t hesitate to contact us for help with new or existing methods.

JY: I became involved in the cannabis testing industry when I came to work for Restek. One of the first projects I worked on was the development of a full workflow solution for the analysis of cannabinoids in lotions, balms, and creams. The cannabis industry is really diverse and it’s a lot of fun to develop new workflows in this market. It’s not solely focused on one type of matrix, so you get to develop methods for a variety of matrices including personal care products, edibles, plant material, concentrates, and more.

JY: From what I’ve seen the cannabis market has seen its hardships just like other industries. Fortunately, retail has still performed well during this pandemic, which has kept a steady revenue stream and demand for product which in turn has kept a demand for testing. However, the growth for expansion and revenue most likely slowed and didn’t reach its full potential. The hardest hit aspect of the cannabis market is likely less expansion and revenue growth for labs. With the US House of Representatives recently passing a bill to decriminalize cannabis, momentum continues to build towards the federal legalization of cannabis. Federal legalization will allow more opportunities for entrepreneurs to invest, more testing labs, and more acceptance for the industry as well. Hopefully, this will result in a path forward for testing standardization. This industry has an exciting future!

Setting a goal is perhaps the easiest step towards carbon neutrality. But the real challenge is in solidifying that goal and starting to make progress towards it. That’s why it’s important to consider how deeply committed each country’s carbon neutral pledge truly is.

In the second step, 100 is equivalent to a 20% standard deviation, which is the average long-term volatility of global equities. Cash would have a RiskGrade of 0, whereas a technology IPO may have a RiskGrade that exceeds 1,000. It should be noted that RiskGrade only captures risk from a market price perspective, and does not consider inflation risk.

Which countries have made a net zero pledge, and how strong is it? This map breaks down carbon neutral pledges.


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Nanoemulsion is the most common method of creating CBD-infused products. The process involves pulverizing cannabinoids into nano-sizes, and combining them with an emulsifier and a carrier oil, in an attempt to create a water-soluble CBD.

Of course, RiskGrades are not static and change over time depending on market conditions. GameStop, which saw heightened volatility as individual investors created a short squeeze, is a strong example of the fluidity of RiskGrades. Based on 5-year intervals, the stock had a RiskGrade of 212 from 2006-2010, and a RiskGrade of 749 from 2016-March 31, 2021—a jump of over 250%.

Health and wellness is emerging as a new reason for cannabis consumption. With Unilever now entering the space with CBD-infused ice cream, the floodgates will open for other major companies to follow suit.