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At a plant level, the two chemicals operate as opposites, with CBD acting as a buffer of sorts to the effects of THC. “It’s sort of a ying and yang. THC is responsible for the high and CBD doesn’t do that,” Hill explains.

According to Low Dog, a tincture may offer a broader range of compounds from hemp than an oil extraction. “Consumers who are alcohol-sensitive often prefer hemp oil over tincture. While both can be used topically, hemp oil is generally easier to apply and less irritating,” she says.

What are tinctures specifically?

“At the end of the day [CBD] is a fairly safe compound,” Hill says. “Although, we still need to know a lot more about it, like how it interacts with other medications people may be taking and what are the long-term effects,” he adds. And perhaps his biggest concern: “Sometimes people want to use it instead of evidence-based treatment and that can be a problem clinically in certain situations.”

“The rate and scale of the research just hasn’t kept pace with the interest at this point. A lot of the medical uses for cannabidiol are backed by animal studies only or really no studies. So that’s where it can be a problem.”

“Sometimes, you will find extracts called tinctures that use glycerin, vinegar, or oil as the solvent, instead of alcohol,” Low Dog says. “These offer the advantage of being alcohol-free, but may not always offer the same potency as an alcohol-water extract.”