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If you’ve still got questions about CBD tinctures, watch Leafly editor Emily Resling discuss the topic a little further in the review below.

Producers like Populum offer several ways to try CBD, including tried and tested tinctures sourced from Colorado-grown cannabis plants and made in the USA. Populum’s signature tincture is available in a variety of strengths, appropriate for dipping a toe into CBD or stepping up a dose to provide more effective relief.

Tinctures are produced by steeping cannabis flowers or isolates in a high-proof grain alcohol, then applying low heat for a significant span of time. This allows the active compounds in cannabis to infuse into the neutral spirit, much of which is then boiled off. The result is a potent liquid that delivers the effects of the cannabinoid molecules without any smoking or other form of combustion. In the growing consumer market, producers will often add carrier oils and other complementary ingredients, such as an orange oil to improve the taste of a tincture.

How to take a tincture

Researchers around the world are investigating CBD’s potential for treating a wide variety of conditions. Near the top of the list is the promise it holds for pain relief. Numerous studies have found that CBD exhibits analgesic and anti-inflammatory properties. These properties make it useful in the treatment of both acute pain—like muscle pulls—and chronic conditions such as arthritis.

When taken to relief the symptoms of epilepsy, CBD is typically administered orally. Researchers have found that this same method of dosing may be effective in using CBD to treat social anxiety disorder, generalized anxiety disorder, and related conditions. Evidence also suggests that this cannabinoid could be helpful in treating the symptoms of obsessive compulsive disorder.

Cannabidiol, more commonly known as CBD, is one of the many identified cannabinoid molecules found in Cannabis plants. Like all cannabinoid molecules, it interacts with the endocannabinoid system in the human body. But because CBD isn’t psychoactive, it doesn’t produce the “high” commonly associated with its more famous cannabinoid cousin, THC. That means that CBD, which is often derived from hemp, or male cannabis plants, doesn’t produce the high that cannabis products are often associated with.

(Courtesy of Populum)

Below is deeper details on all of our top picks, along with what we liked, didn’t like, and where to get them.

Overall, we found 6 American made CBD oil brands that really stood out from the competition, which was over 20 brands in total. In particular, we were really impressed by Spruce – a relative newcomer on the market that is great for all types of relief and helped me immediately cure my restless leg syndrome. We broke down our top picks into a few different categories: overall relief, full spectrum, flavored oils, THC free options, affordability, and product selections. Check out our recommendations below and everything else that we evaluated about each product.

Recommendations: Going Deeper

Green Roads has a massive CBD product selection that can be a bit overwhelming, but they do a good job of laying out all of the information about their products so you can make a good decision on what’s right for you. In addition to their drops, they also offer edibles, capsules, topical creams, and other CBD varieties. Our recommendation is their 50 mg/ML CBD oil, which has good lab test results and should be effective for several types of relief in most people (everyone is different, however). For every single batch of their CBD tinctures, they link to the exact lab sheet results right from their product pages. They also list a ton of great information around compliance, safety, and answer frequently asked questions about each product. In terms of relief, Green Roads has done a good job of solving a lot of different issues from arthritis to anxiety and others.

CBD (cannabidiol) has significantly risen in popularity over the several years, and with good reason. CBD occurs naturally in cannabis plants and the oil can be a really effective solution for several types of relief. CBD oil can help everything from anxiety to pain relief, sleeping disorders, stress reduction, and other issues that our bodies deal with on a day-to-day basis. So, we did the research to find out which manufacturers are making the best CBD oil in the USA. Typically, CBD is taken in one of two forms – drops (tinctures) or topical creams. We’ll focus on drops this time around. Our findings and the factors that went into our research are below. Let us know if you have any questions!

Things we don’t like:

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