For patients interested in CBD oil for the acute treatment of migraine, Dr. Silberstein says it is important to ensure that you are using a pure product. You are likely to receive a pure and safe product in states where CBD oil is legal and grown. Local dispensaries will also be of use in determining origin and quality.
Cannabidiol has taken the U.S. by storm recently. Commonly known as CBD, the active ingredient found in the cannabis, or marijuana, plant, is becoming increasingly available through online retailers, with claims of pain and inflammation reduction. And those living with migraine have taken notice.
Dr. Silberstein advises against obtaining a product in states in which CBD oil is not currently legal or regulated. Illegal forms of CBD oil could be spiked with artificial THC which could be very harmful to patients. Additionally, there are legal implications if you attempt to purchase it where it is currently illegal, so it is important to speak with your healthcare provider and check your local and state laws.
The Effects of CBD
Before beginning any treatment, it is important that you consult your healthcare provider and be open and honest about your plans. Having a strong doctor-patient relationship is key to establishing trust and determining an effective treatment plan that takes into account your lifestyle. “These drugs do interact with the body,” Dr. Silberstein says. “If you’re getting funny symptoms and you’re taking something that the doctor doesn’t know about, how’s he going to help you?”
There is no scientific evidence or research on CBD as an effective treatment for migraine—in large part because it has not been formally studied. However, it may still be a viable topical option for some patients with joint and muscle pain associated with migraine. “If you have a lot of neck pain or soreness, it is perfectly reasonable to use CBD oil. It may even prevent nausea and vomiting,” Dr. Silberstein says.
Dr. Silberstein also cautions against CBD oil or marijuana in use in adolescents, as it may affect the developing brain. “In general, it should be avoided by adolescents until more research has been conducted,” he adds.
Unlike THC, another widely known derivative of the cannabis plant, CBD oil does not have psychoactive properties or effects. “It works locally, and even if taken orally, it won’t produce intoxication,” says Dr. Silberstein.
Although Axon’s study was conducted without the scientific rigor of gold-standard clinical trials, the results of the Hit-6 survey underscore the need for more research into CBD as a possible treatment for migraine sufferers around the world.
Photo courtesy of Axon Relief
Another participant in the study said that the CBD formulation “has significantly helped with my chronic migraines. If taken at onset, I can rely on it to take the edge off relatively quickly.”
One Billion Migraine Sufferers Worldwide
An overwhelming majority of migraine sufferers found relief with the use of CBD oil, according to the results of a recent study. Data from a clinically validated survey showed that 86% of respondents reported a decrease in headache impact after using a cannabidiol (CBD) formulation for a 30-day trial period.
Migraine is one of the world’s most prevalent neurological diseases, according to information from the Migraine Research Foundation, affecting approximately 39 million people in the U.S. and about one billion globally. Symptoms, which are often disabling, can include severe headache, dizziness, nausea, visual disturbances and severe sensitivity to light or sound. Migraine disease is commonly treated with strong pharmaceutical drugs, although with varying results.
The Axon CBD oil used in the migraine study.
“Our goal is to explore if our CBD isolate can help people who suffer from chronic headaches, like migraine. The results of the survey are promising,” Ben Rollins, the founder of Axon Relief, said in a press release.
A 2019 review published in “Current Opinion in Neurology” suggests that CBD may have a role to play in alleviating the pain associated with migraines. CBD can affect the function and activity of signaling pathways by targeting the receptors that play a role in pain control.
There is clinical evidence that suggests this hypothesis could hold validity. A 2007 study published in the journal “Neuropsychopharmacology” showed evidence of depressed anandamide levels in the cerebrospinal fluid of migraine sufferers. Low anandamide levels are a possible indication of an impaired ECS. These findings point to cannabinoids as a potential therapy for chronic migraine sufferers.
Current research indicates that migraines occur when the threshold for pain signaling drops in response to inflammatory agents. Environmental and hormonal triggers most likely initiate the onset of a migraine. Migraine medication often provokes adverse effects, which has resulted in a reduction of research into migraine drugs.
Shelly Schneider, 39, is the president of a busy CBD e-commerce store and a mother. She first began to experience migraines while she was in college in 2003, which she attributes to ongoing stress and tension.
“We use CBD topically in the area of the neck with good results. We’re uncertain as to the benefit of CBD taken orally for migraines, however.” This may be because CBD ingested orally has limited bioavailability.