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cbd salve for pustulate psoriasis

Ultimately, psoriasis is a disorder of the immune system. Part of the cause involves the migration of T cells into the dermis, triggering the release of substances such as cytokines that contribute to local inflammation and keratinocyte proliferation.

CBD can help with various health conditions, including psoriasis, due to the way it acts upon the body. CBD interacts with the body’s endocannabinoid system receptors—CB1 and CB2—in an indirect fashion, and also binds to vanilloid, serotonin, PPARs, and GPR55 receptors.

It appears that the main function of the endocannabinoid system of the skin is to maintain homeostasis. When this balance is thrown off, conditions of the skin, such as psoriasis, can occur. It appears that the anti-inflammatory action of CBD can help to contribute to homeostasis.


There are numerous causes of psoriasis. The condition has a strong genetic component and is known to run in the family. The condition can be triggered in those who are genetically susceptible via trauma, infection, and medications, to name a few. Certain conditions of the kidneys and liver have also been associated with the condition, as has emotional stress.

Anandamide, an endocannabinoid, has been shown to be beneficial by suppressing pathogenic T cell subsets, which are associated with inflammatory skin diseases. Incredibly, CBD has been shown to inhibit anandamide reuptake, blocking the endocannabinoid from being reabsorbed.

Its non-psychoactive nature has also led to the cannabinoid becoming widely available in countries that have outlawed THC-rich cannabis due to its psychoactive effects. CBD gives people in these regions the chance to utilise cannabis medicine without breaking the law.

A paper published within the journal Trends In Pharmacological Sciences states that this system plays a fundamental role within the health of the skin, where it is implicated in numerous biological processes including cell proliferation, growth, differentiation, apoptosis, and hormone production.

In addition to helping to treat skin itching and irritation, CBD may also help psoriasis patients control pain and reduce inflammation.

In the study, five psoriasis patients applied CBD ointment to those areas of their skin affected by psoriasis twice a day for three months. After that time, researchers concluded that the ointment was not only safe and effective but it improved the quality of life for psoriasis patients.

“The effects of cannabis are relatively weak compared to topical steroids like hydrocortisone,” says Dr. Tishler. “In short, at this time I would not recommend any topical cannabis or CBD products to treat a serious illness like psoriasis.”

What we need to learn about how CBD might work

In the end, since the exact nature of how CBD works to help treat psoriasis remains unknown and psoriasis is a serious skin condition, consider this our best advice: Until more studies are done on CBD and psoriasis, be sure to speak with your dermatologist to plan a treatment course that’s right for you.

Another very small study of psoriasis patients conducted in 2019 is equally compelling. The study was led by researchers in Italy and showed that applying topical CBD-enriched ointment on psoriatic skin did help to reduce psoriasis symptoms.

In fact, the preliminary science investigating the ways that CBD, the non-psychoactive part of the marijuana plant, can help treat eczema and psoriasis shows some promise, says Jordan Tishler, MD, a physician and cannabis expert in Boston.

With all of the headlines pointing to the healing powers of cannabidiol (CBD)—one of more than 80 chemical compounds in the cannabis plant—it’s natural to wonder: Can using CBD oil help relieve psoriasis symptoms?

Recent studies into the endocannabinoid system show that it is present throughout the skin. Hence, there’s growing interest in using cannabis-based therapies in the treatment of all kinds of skin conditions, including psoriasis.

A few years ago, the idea of using CBD as a potential treatment was one met with a lot of scrutiny. Today, however, there’s a growing body of research proving its efficacy in soothing all kinds of conditions and symptoms, including dermatological ailments like psoriasis.

Can CBD Help With Psoriasis?

What, exactly, causes the abnormal growth of skin in psoriasis, however, isn’t clear. So far, researchers suggest it could come down to genetics. Some patients, on the other hand, may suddenly develop psoriasis as a response to a trigger, such as an injury, viral infection, or environmental change. Some possible triggers of psoriasis include:

We suggest sourcing full-spectrum CBD topicals, as they contain an array of cannabinoids and terpenes in addition to CBD. As suggested in the above studies, CBD isn’t the only cannabis constituent that appears to be potentially beneficial for the skin.

Psoriasis is categorised depending on the location it affects and the symptoms it produces. The most common form of psoriasis is plaque psoriasis, which causes dry, red lesions typically on the elbows, knees, lower back, and scalp. Inverse psoriasis, on the other hand, affects skin folds in the groin, under the breasts and buttocks, and causes smooth patches of red skin.