CBD also interacts with other receptor proteins not directly related to the ECS, such as the serotonin receptor 5-HT1A and vanilloid receptor TRPV1. Any potential anti-inflammatory and pain-relieving properties of CBD could stem from the activation of these additional biological pathways.
Bottom line: Expect to feel the effects of sublingual administration within 30 minutes. Any effects you feel should last an hour or more but be bolstered at about two hours.
The method of consumption matters
Whether you’re smoking a high-CBD strain, puffing on a hemp flower pre-roll, or taking a draw from a CBD vape pen, inhalation is often seen as an effective method of delivery for CBD because of how quickly it’s absorbed in the body. When you smoke CBD flower or vape CBD oil, cannabinoids go directly to your lungs where they rapidly enter your bloodstream and circulate throughout your body. CBD reaches peak concentrations within three minutes after consumption, meaning the effects can be felt shortly after use.
Administering a couple of drops of CBD oil directly under the tongue is the quickest and easiest way to reap the potential benefits. Photo by: Gina Coleman/Weedmaps
It’s not just your body that influences how long it takes CBD to work, but also the quality of the CBD product and how often it’s used. Once you acquire CBD oil, the next step is to find the optimal dosing regimen, including frequency of use. The answers will depend largely on the type of product, amount of CBD inside it, and the specific ailment you are targeting. Most reputable manufacturers will provide instructions on how to properly use the product, but experimentation may be required to find the optimal dose for you and your specific needs.
So, be patient and experiment while listening to your body, and you are likely to get the benefits you are looking for.
You can read more about dosing in our guide: How much CBD oil should I take
It’s very important to remember, that what dose works for one person might not work for the next.
Tips for making sure you get the most out of your CBD experience:
If a person has been taking CBD for an extended period of time and not getting the results they are looking for, chances are they are not taking a high enough dose. The general recommendation for dosing, is to start low (5mg per day) and go slow – gradually working up the dose every five to seven days.
Vaping or smoking CBD flower, however is usually felt within minutes, and gives more of an uplifted feeling, but also doesn’t last as long. The effects of smoking CBD are usually felt for an hour or two.
For more “extreme” issues such as depression, anxiety, and chronic pain you might need as high as a 60mg daily dose.
For somebody that isn’t struggling with major inflammation, or mental health issues, a 10mg daily serving at night should be enough for most people to sleep better, but occasionally more might be needed.
The way CBD interacts with your body is also dependent upon factors that change from person to person. These include your body weight and metabolism.
CBD, or cannabidiol, is a cannabinoid found in the hemp plant that works with your body’s endocannabinoid system. The effects of CBD are non-psychoactive, so we can use CBD for a variety of reasons and consume it in multiple forms.
Once you’ve consumed a recommended serving of CBD, it will begin interacting with your endocannabinoid system (ECS). For this to occur, special receptors in the ECS have to accept CBD and allow it to interact with your body. They’re called your CB1 and CB2 receptors.
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Depending on your consumption method, the effects of CBD will last for 2-4 hours. Of the many consumption options that exist, CBD topicals will last the longest simply because it takes the skin longer to absorb CBD. However, absorbing it through the tongue, such as with a CBD tincture, will tend to work the fastest.
Vaping CBD is the process of inhaling vaporized CBD oil contained in a cartridge or pen designed for that purpose. When you inhale CBD, it enters your bloodstream through the lungs. While little data exists to suggest how long it takes to feel the effects, since CBD gets to the bloodstream fairly quickly and from there can be distributed throughout the body, you should feel the effects within 2-5 minutes.
To understand how CBD will interact with your body, it pays to start small and work your way up. If it’s your first time or you’re new to CBD, follow a process of trial and error to determine which CBD product meets your needs, always making sure you’re purchasing something that’s high quality. From there, you can fine-tune your dosage until you’re receiving the desired effects.