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cbd oil pregnancy

The researchers are continuing to draw the epigenetic map of gestational CBD exposure and its impact on youth and adults. In the future, they hope to expand behavioral studies to include measures of sociability and drug reward, which are important for diseases like autism spectrum disorder and substance use disorder, respectively. They also plan to repeat these measurements in adolescent offspring in order to determine whether abnormalities are already present at an earlier age or whether they develop later.

Among the study’s key findings:

The research team, made up of scientists at the University of Minnesota’s Department of Animal Science and College of Veterinary Medicine, began by using a human-relevant dose that is typical in adults purchasing CBD over the counter for a variety of ailments. Next, the team treated pregnant mice daily throughout pregnancy and lactation until the pups were weaned. The offspring were followed into adulthood without any additional CBD, at which time they were measured for persistent behavioral and molecular impacts of CBD.

Specifically, the team of scientists investigated rodent behavior and DNA methylation, an important mechanism known as an epigenetic mark in both rodents and humans that helps control the “when, where, and how much” of gene activity. CBD’s effects on gene activity markers were examined in two brain regions important for memory, mood, and cognition.

According to Faulk and Wanner, gaining more insight into how CBD affects the developing brain will be important for future safety recommendations.

“CBD use has exploded in recent years, yet we still don’t have a clear picture of its impact on the brain, especially during development,” said study director Christopher Faulk, an assistant professor in the College of Food, Agricultural and Natural Resource Sciences. “We show here that use during pregnancy can permanently impact the resulting offspring in adulthood and potentially for the rest of their lives.”

The use of cannabidiol (CBD), the major non-psychoactive compound in cannabis, is on the rise across the United States. Pregnant women in particular may view CBD as more “natural” than other remedies for concerns such as nausea and pain, but the consequences of use for the developing fetus are unknown.

For one thing, we need a lot more research into the effects of CBD on pregnant mothers and unborn babies. Experts mainly have animal studies to go on. For instance, researchers who gave pregnant test animals high doses of CBD noticed problems in the reproductive systems of male fetuses. That doesn’t necessarily mean the same thing would happen in people, but the FDA says it’s concerned by the finding.

It’s also possible for CBD products to be contaminated with things that could be dangerous for a developing or nursing baby, like THC. That’s the chemical in cannabis that gets you high. Experts advise all women to avoid THC while pregnant and breastfeeding. It may affect a baby’s brain development in the womb. It can also raise the chances of stillbirth or premature birth. THC can pass to an infant through breast milk, and experts think this can happen with CBD as well.

Why It’s Risky

What’s more, studies show that CBD poses risks for everyone, like liver damage and extreme sleepiness. It could also hurt your health by affecting medications you take.

FDA: “What You Should Know About Using Cannabis, Including CBD, When Pregnant or Breastfeeding,” “FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy.”

If you’re having pregnancy symptoms, maybe you’ve wondered if CBD (cannabidiol) can bring you relief. CBD is a compound in marijuana and hemp that doesn’t get you high. And products with CBD in it are becoming more and more popular. Manufacturers use it in things like foods, drinks, beauty products, and supplements.