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Configured as a continuous milling system, the PULVERISETTE 14 classic line with Cyclone allows continuous feeding of material, and active removal of material from the rotor area – typically within a fraction of a second. Because the homogenization occurs so quickly and the material is actively removed, there is no time for frictional temperature increase to occur that could cause chemical degradation. Product contact surfaces are stainless steel, or food-grade plastic vacuum hose for the Cyclone, and can all be cleaned thoroughly between batches to reduce the likelihood of cross-contamination. Variable speed motor and range of sieve rings, provides control of particle size output. Used together with collection vessel, the PULVERISETTE 14 classic line and Cyclone separator allow continuous feeding and homogenization of CBD material into the low micron range (consistency of talcum powder).
Production-scale homogenization of CBD isolate into uniform powder can be achieved with the FRITSCH Universal Cutting Mill PULVERISETTE 19. Already considered the premier, precision milling solution for preparation of cannabis biomass for extractions, or pre-roll products, the cutting mill may be configured as a large-scale homogenizer to allow continuous processing of large batches of isolate material.
Primary considerations when selecting a milling system for CBD homogenization include:
• Gap setting between cutting rotor & fixed knives: 1 – 2 mm
• Rotor with notched edges and fixed knives
•Minimizing losses (physical and/or chemical)
Add to this, the proportion of these Different parts of the plant (eg: flowers from the top or flowers from the bottom of the plant), different plants, different locations and methods of cultivation, time of harvesting, and drying, curing and processing methods.
Pharmaceutical drugs typically contain an active ingredient along with a number of “inactive” ingredients which function as fillers, diluents, carriers, stabilisers, taste modifiers etc.
CBD Isolate’s most promising use is as a pharmaceutical ingredient in the treatment of various serious diseases, including diseases where other treatments are ineffective.
Benefits of CBD Isolate as a Botanical Extract
Of all cannabinoids studied to date, CBD has shown the widest range of benefits, though this could be due to the lack of research on lesser known compounds. Regardless, it demonstrates a remarkable amount of medical promise for any “new” or existing drug category.
CBD shows great promise as a treatment for an incredibly wide range of diseases. This diversity of impact is due to it’s impact on the EndoCannabinoid System – a vital homeostatic system regulating many aspects of human and animal health including inflammation, immune function and neurologic activity.
On June 25, 2018, the United States Food & Drug Administration (FDA) approved CBD Isolate drug EPIDIOLEX® for use in the treatment of seizures associated with two severe epilepsy syndromes – Lennox-Gastaut syndromeand Dravet syndrome.
All these factors are well understood in medicinal herbs but scary and unworkable for the pharmaceutical industry.