Potential drug-drug interactions with CBD include:
In an analysis of 14 published studies (nine involving animals and five involving humans), scientists with the University of Montreal concluded that CBD showed promise in treating people with opioid, cocaine, or psychostimulant addiction.
There are no guidelines for the appropriate use of CBD oil. CBD oil is usually delivered sublingually (under the tongue). Most oils are sold in 30-milliliter (mL) bottles with a dropper cap.
Dosage and Preparation
Common symptoms include:
The tricky part is calculating the exact amount of CBD per milliliter of oil. Some tinctures have concentrations of 1,500 mg per 30 mL, while others have 3,000 mg per mL (or more).
Here is just some of what the current evidence says.
CBD is the short name for cannabidiol, one of the two chemicals—among the dozens in cannabis—that have the most health benefits. The other, tetrahydrocannabinol (THC), produces the psychoactive effects described as being “high.” CBD oil generally does not contain THC, although some trace amounts may be present in products sold in certain states.
As such, many people use CBD to supplement, or even as an alternative to, prescribed medications. A huge bonus of using CBD for these ends is that it possesses fewer side effects and doesn’t lead to a possible dependence.
CBD isolate is the third type of CBD refinement. This refers to a product that solely contains cannabidiol, and is the purest variety of CBD on the market, as all other elements are completely removed during the extraction process.
CBD & Sleep
Due to ethical reasons, testing the safety of CBD in children and pregnant women is extremely rare, meaning there are few studies out there to inform us about its effects and potential dangers. Nevertheless, if we take the testing of Epidiolex as an example, this examined the reactions of children with epilepsy after taking CBD for their condition. The fact that today, Epidiolex is approved as a prescription drug in many parts of the world for children over the age of two speaks for itself. That’s not to say that we should start giving CBD products to children, though, unless absolutely necessary and approved by a doctor.
Individuals who suffer from liver problems might need to be cautious about their CBD intake. It is currently unclear whether CBD products directly affect the liver or interact with pharmaceuticals associated with liver problems. Monitoring liver enzymes is highly recommended when introducing CBD into your daily routine. Avoiding CBD altogether or sticking to microdoses may be advisable.
CBD is most commonly found in the form of oil, and can be ingested, inhaled or applied topically. Those are not the only ways to administer this cannabinoid, however. Increasingly, there are various ways to get CBD into your system and multiple formats in which CBD can be found.
The most comment side effects of CBD include drowsiness, gastrointestinal issues, dry mouth, reduced appetite, nausea, and interaction with other medications. Those are outlined in detail below.
CBD is one of the many chemical compounds that is found in the cannabis plant—referred to as cannabis sativa. There are two primary parts of the plant that humans use. One is THC, or Delta-9-Tetrahydrocannabinol, and the other is CBD. Though they’re from the same plant, THC and CBD are quite different from each other.
Some common side effects when using CBD include drowsiness and sedation. This is also considered a benefit, but Dr. Jas Matharu-Daley, a physician and chief medical officer for a CBD brand, notes that the effects might be too strong if you’re also taking CBD with other sedating medications.
“If the CBD is from a reputable source and one that has been inspected by a third-party independent lab, the content of CBD is more reliable,” notes Dr. Matharu-Daley. “The CBD should be organically grown, free of pesticides and heavy metals, and not sourced in food which can affect absorption. Generally, CBD is safe and side effects are few at low doses.”
Ultimately, the primary reasons why people use CBD is because it tends to have calming, relaxing, pain-reducing effects. It has been used to alleviate joint pain and nerve pain, reduce anxiety and stress, treat insomnia, improve migraines, and address nausea.