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cbd cream vs a535

More recent research suggests that many of CBD’s effects may occur outside of CB receptors, Jordan Tishler, M.D., medical cannabis expert at InhaleMD in Boston, tells SELF. In fact, according to a recent review published in Molecules, CBD may have effects on some serotonin receptors (known to play a role in depression and anxiety), adenosine receptors (one of the neurological targets for caffeine), and even TRPV-1 receptors (more commonly associated with taste and the sensation of spiciness).

It’s also important to remember that, although generally benign, side effects have been reported with some forms of CBD. For instance, oral CBD taken in the large amounts that have shown some limited promise in helping with anxiety issues may come with side effects, such as diarrhea, reduced appetite, fatigue, and interactions with other drugs you might be taking, specifically blood thinners, Cooper says.

What is CBD?

“It actually is a very promiscuous compound,” Kevin Boehnke, Ph.D., research fellow in the department of anesthesiology and the Chronic Pain and Fatigue Research Center at the University of Michigan, tells SELF. “It will bind to receptors in multiple different pathways,” which makes it difficult to know how it might cause noticeable effects.

Two other common reasons people take CBD are to manage anxiety and sleep issues, two things we know can contribute to pain, Boehnke says. If you're dealing those kinds of issues in addition to pain, any reduction in pain you feel could be an indirect effect of it helping you manage anxiety or sleep. (But those are still unlikely to be affected by a topical formulation.)

Nevertheless, how do we account for all the people out there (like me) who use these products and feel like they’re doing something? Beyond the placebo effect, it’s possible that something else in the cream could be doing the heavy lifting here. These products don’t just contain CBD, Dr. Tishler points out. In fact, many of them also come with ingredients like arnica, menthol, or camphor, which may all provide a more immediate sensation of soothing or pain relief. So it could be those ingredients (or just the act of massaging the balm into your skin) that makes you feel better.

Perhaps most importantly, the effectiveness of CBD pain relief rubs for a variety of pain conditions is totally scientifically plausible. CBD is known for being an anti-inflammatory agent; this has been proven again and again. We just need to have more studies to validate anecdotal evidence and scientific plausibility.

Many patients find that using a CBD topical with tinctures or capsules dramatically improves their results. Combining methods can also be especially useful if you’re dealing with a painful acute flare-up. And remember: one of the advantages of CBD pain relief rubs is that unlike opioids or other pain relief drugs, you can’t overdose on it, nor is it addictive or habit-forming.

Is There Any Risk in Trying CBD Pain Relief Rubs?

There’s no “best” type of product or best intake method, generally speaking. But there is a “best” product type for you. The best product is what works well for you and aligns with your objectives. Likewise, the optimal dose is the lowest dose you can administer that provides the most relief with the fewest side effects.

According to one study published by the Journal of Pain Research suggested many topical cannabinoid treatments reduced pain in animals suffering from neuropathic pain or inflammation. Likewise, other research suggests THC and CBD-infused topical rubs can relieve pain not only for arthritis or muscle soreness but conditions like multiple sclerosis (MS).

“In adults with chronic pain, patients who were treated with cannabis or cannabinoids are more likely to experience a clinically significant reduction in pain symptoms.”

The simplest topical is the one you already have in your medicine cabinet. Simply take your favourite cannabis oil and apply to it the area that hurts, avoiding the ears, eyes and genital areas . “Apply liberally and massage it in well, like you would any other pain-relieving cream, such as A535,” says Natural Care nurse Karen Newell.

Anecdotally, topicals are useful for localized pain relief, soreness, inflammation and more. Recent studies indicate they may be useful in treating inflammatory and neuropathic pain, skin allergies, psoriasis, dermatitis, arthritis, mild skin irritations and more. Many people are also using topicals in the form of lubricants for enhanced sexual pleasure.

Topicals are a hot topic these days. Unfortunately, the cannabis-infused creams, lotions, salves and bath products won’t be available for legal purchase until new amendments to the Cannabis Act take effect in October 2019. Until then, it’s perfectly legal to turn your favourite cannabis oil into a simple do-it-yourself cream by following the recipe below.

What symptoms do topicals treat?

To extend value and save money, some people prefer to mix their cannabis oil with an existing cream, lotion or oil, such as coconut, olive or almond oil. Once mixed, follow the same process as above, applying liberally and massaging well.

That’s all it takes! If you decide to try this simple recipe, please let us know how it’s going at your next check-in with your Natural Care nurse or educator.

In most cases, even if a topical contains THC, it’s unlikely to induce the intoxicating effects you’d expect from swallowing or inhaling an equivalent amount. This is because the cannabinoids can’t breach the bloodstream through the skin. (It’s worth noting that some transdermal patches can deliver cannabinoids into the bloodstream and induce intoxicating effects, but these products are not yet legally available in Canada).

Currently, Health Canada does not permit the sale of cannabis creams, although some licensed producers (LPs) sell pre-made creams that can be mixed with their oils for legal home use.