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cbd cream and drug interactions

CBD influences a class of drug-metabolizing enzymes in the Cytochrome P450 family, also known as CYP450. These enzymes are involved in metabolizing over 60 percent of all pharmaceuticals.

There are a variety of ways to use CBD oil, and your usage will vary depending on your lifestyle and health goals. The various modes of administration will also impact how long it takes for CBD to work.

CBD vape oil is generally bonded with vegetable glycerin (VG) to make it more vaporizer-friendly. Some vape compatible CBD oil can be also be mixed with other vape juice.

The Cytochrome P450 Family

Prescribed drugs are commonplace in modern society, and the acceptance of cannabis is on the rise. It’s important to be aware of potential drug interactions with cannabinoids like CBD (cannabidiol) and THC (tetrahydrocannabinol).

If the cannabinoid induces a CYP enzyme, it will shorten the lifespan of the second drug due to more of that enzyme being made.

Any potential cannabinoid-drug interactions will likely occur in minutes. Inhaled cannabinoids interact with the CYP1 family of enzymes.

CBD is most widely known and has been popularized as being used for seizure disorders such as epilepsy, but has also proven to be effective in helping to relieve the symptoms of other conditions. These include anxiety, depression, schizophrenia, inflammatory and neuropathic pain, Parkinson’s disease, Crohn’s and other forms of inflammatory bowel disease, as well as certain types of cancer.

Let’s find out why.

Understanding Metabolism

However, in addition to breaking compounds down into metabolites, is also has one other very specific and important role it plays during this metabolic process – the detoxification and excretion of foreign drugs (called xenobiotics) and other types of toxic substances.

It does through a system called the cytochrome P450 system (CYP) which consists of a special group of enzymes containing heme as a cofactor to convert fat-soluble compounds into more water-soluble compounds and aiding in their absorption and use.

A lot of people think of metabolism in terms of how easily or slowly they gain and lose weight, often claiming to have a “fast” or “slow” metabolism. In scientific terms, this is what is known as the basal metabolic rate, or the amount of calories an individual requires in order to sustain normal body functions while at rest.