Second, when an organic compound like CBD enters your gut, it has to pass through the liver before it enters your circulation. During this transition, the liver will actively reduce the amount of CBD, either through absorption or through chemical breakdown by liver enzymes. This phenomenon is called the “first-pass effect,” where passing through the liver reduces the concentration of bioactive compounds.
Of course, if you’re leaning towards embracing the vape life, make sure you’ve done your research on the concentrate you intend to consume. Without sufficient regulatory oversight in the emerging vape and cannabis industries, few companies have been able to produce a clear and homogenous CBD solution, so the milligram amount in CBD products is often inconsistent with the amount claimed on the label. Be sure to ask for both in-house and third-party test results from your chosen source to ensure you’re getting a quality product!
“There’s more than one way to skin a cat” is a weirdly morbid saying, but the phrase’s core concept rings true – there are a lot of ways to accomplish the same task. This has never been more true for cannabidiol (CBD). With the rising demand for CBD products, there are a plethora of different ways to get your daily dose. They range from sublingual sprays, to vaping CBD oils, to smoking good old-fashioned joints. Yet most people don’t know that the way in which you ingest CBD can drastically alter its effective dosage.
CBD’s Bioavailability: Understanding Its Variations
There are a few different ways to offset these losses of CBD. For one, you can reduce the amount of CBD that dissolves out of your bloodstream by putting the CBD into a form that is more hydrophilic, or water-soluble. However, this can only be achieved by complicated chemical means, such as through the use of cyclodextrins or liposomes. A more practical solution is to bypass the first-pass effect of oral administration entirely by utilizing vaporization.
This article is sponsored by CV Sciences, Inc. CV Sciences is one of the leading suppliers and manufacturers of agricultural hemp-derived CBD bulk and finished products, namely their PlusCBD Oil and Purified Liquids brands.
Not only that, but vaping will greatly decrease the amount of time it takes for the CBD in your body to become active, since you don’t have to wait for it to travel through your gut. By vaporizing a CBD e-liquid or high-CBD concentrate, you could potentially feel its effects 30 to 60 minutes faster. This makes vaping CBD an extremely efficient delivery method.
During vaporization, CBD enters your lungs and diffuses directly into your bloodstream rather than passing through your gut and liver. This avoids the first-pass effect altogether, allowing nearly four times as much CBD to enter your circulation for a maximum bioavailability of roughly 50 to 60 percent. Essentially, this means you can achieve the same beneficial effects with a much smaller amount of CBD.
Lab tests are conducted to verify cannabinoid content, THC levels, residual solvents and contaminants. Always make sure they’re up to date (preferably from within the last nine months) and are from a credible lab. You might feel intimidated when looking at some of the technical data in the report. Don’t worry, the THC and CBD levels are usually bold and easy to identify. You want to look for “Max Active THC” and “Max Active CBD” to determine the levels of THC and CBD. They are generally represented in “mg per mL,” “mg per bottle,” and as an overall percentage, which is useful for calculating dosages.
Furthermore, CBD can actually moderate the high that THC produces, by preventing your body from fully breaking the THC down. If you ever find yourself “too high,” Take CBD oil for anxiety. It helps level you out and can also reduce the paranoia caused by THC.
The average CBD user takes an average of 10-30 mg per day. For serious conditions like pain and inflammation, some users take as much as 200-1000 mg per day. See our full guide for more specifics on how to determine your ideal CBD dosage.
Why are lab tests so important?
CBD, short for cannabidiol, is a naturally-occurring cannabinoid found in hemp, a type of cannabis plant. Cannabidiol is known for its therapeutic properties and has been growing in popularity in recent years. CBD oil has a range of benefits used to relieve symptoms associated with inflammation, anxiety, depression, pain and epilepsy. CBD can be infused into a variety of products including vape juice, edibles and CBD oil tinctures, capsules and creams.
Unfortunately, there is no “one-size-fits-all” dosage for CBD. It greatly depends on a range of factors, including the symptoms being treated, body weight and tolerance. In addition, everyone’s metabolism and endocannabinoid system is slightly different, which can yield unique results for each person.
Research has shown that CBD is very low in toxicity. A study from 1981 determined the LD50 for CBD to be 212 mg per kg of body weight when given to monkeys intravenously. This suggests that humans must consume hundreds of times the average daily dose of CBD (30 mg) in a relatively short period of time to be at risk for overdosing. It is highly unlikely that anybody will ever take enough cannabidiol to induce lethal consequences.
Vaping CBD is not the only way to take it, but it happens to be one of the best. There are many other alternatives such as oral tinctures, creams, CBD patches, CBD drinks, CBD isolate powder, and CBD capsules and edibles. CBD crystal isolate powder is ideal for making edibles since it typically contains 99% pure CBD. The crystals dissolve into butter or oil, and can be used to create CBD-infused butter, or any of your favorite recipes.
When you inhale CBD vape, the CBD is inhaled into the lungs and vaporized into tiny mist particles that pass through membranes and are very quickly distributed into the bloodstream. Many claim to feel the effects in as little as 30 seconds to a few minutes. But the effects are typically shorter lived compared to CBD oil, lasting about 3-5 hours.
CBD has quickly gone from 3 random letters to a much talked about new holistic compound. This rise in popularity also means a wider variety of CBD products are available to purchase. This leaves many new users confused. If you’re one of the many confused peeps who are wondering if you should buy CBD oil or a CBD vape pen , read on! This article is for you.
Personally, I like to do a mixture of both our CBD Oil and CBD Vape. I am a professional athlete, so I put a lot of stress on my body. I’ve found that micro-dosing and keeping a steady dose of CBD in my system has been most beneficial for me. I like to use my CBD Oil sublingual first thing in the morning and then again before bed. The pens have been a great way for me to get CBD as needed in-between oil doses.
Before we dive into the difference in delivery methods, let’s talk about how our CBD products here at Ignite are the same .
Understanding the “best” way to take CBD can certainly be overwhelming. But when trying anything new, there’s always a learning curve- CBD is no different.
We should point out that because CBD is still relatively new in terms of being researched it is still very under-studied. Much of the information you find online in terms of delivery method and bioavailability is based on short term studies and lots of opinions. We look forward to more research being done in the future. For now, know that everyone is different and you are likely going to have to experiment a little to determine which delivery method works best for you.
In short: CBD oil can take longer to feel the effects, but typically lasts longer. This means you may only need to take it 1-2x per day. If you plan on taking CBD every single day, then a high-concentration, long-lasting sublingual drops may suit you well.