Despite the success stories, there’s surprisingly little scientific research about CBD’s efficacy, safety, and appropriate dosing, says Salomeh Keyhani, M.D., a professor at the University of California, San Francisco, who has published research on medical marijuana use. She says that while there is some research showing that cannabis products may help manage a few specific health conditions, for most benefits touted on the internet “there’s often little or no evidence.”
Also, cannabis plants contain other compounds (often referred to as cannabinoids) that could be in your CBD product. The most notable one, of course, is THC, which can alter your cognition and have long-term effects on learning and memory loss, according to the American Academy of Neurology. So look for a product that says it contains only CBD rather than “cannabinoids,” which could indicate the presence of other compounds, such as THC. CBD-only products should contain no THC, or minuscule amounts.
Americans are turning to this cannabis product for its possible health benefits, despite little guidance on how to use it
Unlike tetrahydrocannabinol (aka THC, the chemical in marijuana responsible for the plant’s mind-altering effects), CBD does not get users high. But it’s gaining popularity as a pain reliever and for its other possible health benefits.
2. Consult with your doctor. Your healthcare provider should be kept informed of all the drugs and supplements you take, including CBD, in order to best manage your overall care, help you determine the best treatment options for your condition, and guard against potential drug interactions and other risks (see below). “Patients are generally reluctant to tell their oncologists about complementary therapies in general for fear of being castigated,” Abrams says. But if you’ve started using CBD, it’s in your best interest to let your doctor know.
“It felt like a wave of warmth went over my body, and the nerve pain almost 100 percent subsided,” Van Dyken says.
A 2011 study performed on mice and published in the British Journal of Pharmacology also shows that CBD has potential nausea-reducing properties, which may help soothe side effects associated with metoprolol.
CYP proteins process Eliquis in the liver, the same proteins on which CBD acts to delay metabolization. This process could cause an overdose of Eliquis’ chemicals in the body and a high risk of severe bleeding.
Patients taking generic warfarin or Coumadin should consult their healthcare provider for individualized information and get blood tests before beginning a CBD regimen.
Should I take CBD with metformin?
Cannabis is a complex plant, with hundreds of chemicals and over 100 distinct cannabinoids. The little research that examines cannabidiol or CBD, the second most common cannabinoid found in cannabis, shows evidence of potential health benefits for a wide range of conditions. As CBD becomes more mainstream, however, a key question comes to mind, “How will CBD interact with my current medication?”
Thyroid medication is used to treat thyroid disorders, most commonly hypothyroidism (an underactive thyroid) via thyroid hormone replacement, and hyperthyroidism (an overactive thyroid) via anti-thyroid medication. Different medications achieve these objectives through different pathways in the body. Side effects of thyroid hormone replacement therapies include chest pain, anxiety, headaches, and vomiting. While rare, anti-thyroid medication side effects can include rash, itching, fever, aches, and headaches.
More research is needed on CBD’s interaction with diabetes. Patients taking metformin should talk to their doctor about whether CBD is right for them.
In 2017, researchers at the University of Alabama, Birmingham, conducted a study published in Epilepsy & Behavior Case Reports which showed that CBD increases the effects of drugs used for blood-thinning by slowing down how the body metabolizes warfarin and prolonging its presence in the system. By increasing the duration of warfarin’s presence in the body, CBD could potentially exacerbate some of the associated risks.
Using CBD with some sleep-inducing supplements can lead to the additive sleepy effect. It does not mean that all CBD users will feel it. But medical experts recommend avoiding combining CBD and herbs causing sleepiness when you have to perform some technical operations.
Some studies found that CBD may increase the effects of medications used for blood thinning like warfarin or drugs with a risk of blood-thinning including ibuprofen 2 .
Some studies found that CBD may interfere with the metabolism of certain anti-seizure drugs in the liver and thus leading to severe interactions.
CBD is known to help in epileptic seizures 4 . But simultaneous usage of CBD with anti-seizure drugs can lead to specific problems.
Thought CBD might potentiate the action of epilepsy drugs, but it may also increase chances of side effects like dizziness, constipation, breathing problems and even depression 5 .
Statins are drugs used to reduce cholesterol levels in the human body and help reduce the risk of heart diseases. Some findings show that statins interact with CBD. If a person uses both frequently, it can lead to the increased concentration of medicines causing dangerous chemical accumulation 3 .
But in most cases, it depends on the individual. Some CBD consumers do not experience any adverse effect after they use both simultaneously. But before combining them, it is better to know your reaction and to play safe; it is recommended to avoid taking CBD with sedatives.