Can you "inject marijuanas," as the satirical memes suggest? Yes, but it’s a really, really stupid thing to do, according to a new study. Cannabis is widely used recreationally and for symptomatic relief in a number of ailments. However, cannabis has been implicated as a risk factor for the development of psychotic illness. For forty years researchers have utilised intravenous preparations of Δ(9)-THC, as well as several other phytoca … Aside from smoking cannabis, there are now concentrates, edibles, transdermal patches, topicals and oils. Cannabis oil is one of the approved ways to ingest medical marijuana. Whether you are looking to make baked goods, infused recipes for drinks, or simply taking the oil sublingually (under the tongue), the possibilities are endless.
Can You Inject CBD Oil
Can you “inject marijuanas,” as the satirical memes suggest? Yes, but it’s a really, really stupid thing to do, according to a new study.
A new study found that injecting pure THC triggered schizophrenia-like behaviors in subjects. But, uh, does anyone actually consume weed this way?
The study, conducted by schizophrenia researchers at the Veterans Affairs Healthcare System in Connecticut, and recently published in Neuropsychopharmacology, involved shooting up 22 healthy individuals with 2.5mg THC, 5mg THC, or a placebo (0mg THC). The subjects had previously been “exposed” to cannabis, but none had been diagnosed with cannabis use disorder.
After three separate days of mainlining pure THC, the subjects reported experiencing schizophrenia-like symptoms, increased anxiety, altered perceptions, euphoria, and a host of memory and speech issues. Their blood also showed increased levels of cortisol, the primary stress hormone. Not surprisingly, the researchers concluded that THC produces psychotic behaviors, and more studies are needed to see how cannabinoid receptors may contribute to psychotic disorders.
Usually when we see anything about injecting THC or “marijuanas,” it comes from satirical social media accounts that claim shooting up weed can cause everything from suddenly turning someone gay to spontaneous death (again, these are memes). But intravenous administration of THC is a standard (though not terribly common) practice in cannabis studies, since it gives researchers precise control over dosing. The only problem with this study and others like it is that no one actually injects pure THC. There’s a reason why most consumers prefer to smoke or vape cannabis, after all.
When someone smokes, let’s say, a one-gram joint rolled with weed containing 25 percent THC, that joint contains, roughly, 250mg of THCA, the form of THC that doesn’t get anyone high. Heat converts some THCA into THC — the stuff that gets people lit — but only some THCA turns into the psychoactive form. The average time that heat is applied to the joint isn’t long enough to convert all of the THCA to THC. Furthermore, a bunch of converted THC gets lost in the smoke that wafts from the joint, and even more THC gets stuck in the ash.
So, by the end of it, even if just one person smoked that entire 1-gram joint to the face, they’re only getting a small fraction of that potential 250mg THC, not to mention a cornucopia of other compounds such as other cannabinoids, terpenes, flavonoids, and polyphenols — which all may interact with our brain’s cannabinoid receptors, dulling the negative effects of THC.
In other words, shooting someone up with 2.5mg or 5mg pure THC is kind of a lot, especially for non-stoners, which this study focused on.
In addition to there being next-to-no people who shoot up THC distillate or diamonds on a regular basis, no one shoots up actual weed, either. Back in the ‘70s and ‘80s, some idiots tried that, and they developed what’s called “intravenously injected marijuana disorder.” Basically, folks would boil weed buds into a “broth,” pull that filtered broth up into a syringe, then inject it. Rather than getting lit, they got sick AF instead, which included bouts of vomiting, intense muscle pains, and serious heart problems.
Here’s the thing about IV marijuana disorder, too: There are practically no new case studies on it after 1986, suggesting that only a handful of people did it back in the day. Why? Obviously, it sucks, and it’s potentially life-threatening. Which is why, today and in the past, folks have stuck to puffing their pot.
Does this mean that everything about the VA study is bogus? Not entirely. We know that the endocannabinoid system plays a role in some mental disorders, and cannabis use can aggravate some psychotic symptoms in people particularly prone to them. However, many cannabis patients consume weed to alleviate symptoms of their personality or mood disorders, too, so the issue isn’t black-and-white, nor is it clear-cut.
Oh, and in case if you’re wondering if you can snort weed, yeah, technically, that’s possible. But you’ll end up blowing pot-snot all day and never catching a buzz.
Cannabis in the arm: what can we learn from intravenous cannabinoid studies?
Cannabis is widely used recreationally and for symptomatic relief in a number of ailments. However, cannabis has been implicated as a risk factor for the development of psychotic illness. For forty years researchers have utilised intravenous preparations of Δ(9)-THC, as well as several other phytocannabinoids, in a laboratory setting. The intravenous route has the most reliable pharmacokinetics, reducing inter-individual variation in bioavailability and is well suited for the delivery of synthetic compounds containing a sole pharmacological moiety. Given the association between cannabinoids and psychotic illness, there has been a resurgence of interest in experimental studies of cannabinoids in humans, and the intravenous route has been employed. Here in a critical review, we appraise the major findings from recent intravenous cannabinoid studies in humans and trace the historical roots of this work back to the 1970’s.
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Best Ways to Use Cannabis Oil
As a Florida medical marijuana patient, there are more options than ever when it comes to cannabis consumption. Aside from smoking cannabis, there are now concentrates, edibles, transdermal patches, topicals and oils. Cannabis oil is one of the approved ways to ingest medical marijuana. Whether you are looking to make baked goods, infused recipes for drinks, or simply taking the oil sublingually (under the tongue), the possibilities are endless.
What is cannabis oil?
Similar to olive, vegetable, and coconut oil, cannabis oil is made through the same chemical extraction process. Cannabis oil is a concentrate made by extracting cannabinoids, such as THC and CBD, from the cannabis plant and putting the extracts into a carrier substance (oil).
How to take cannabis oil
There are numerous ways to take cannabis oil that are safe and effective. Here are a few popular ways to help you find relief:
Under the tongue
Cannabis oil is generally taken sublingually, where it is absorbed by the mucous membrane under the tongue, eventually making its way into the bloodstream. Unlike pills or other forms of drugs, sublingual medications can enter the bloodstream rapidly and in high concentrations, due to the high vascularity of the cheeks and gums. A few benefits of sublingual marijuana include:
- No smell associated with it
- Very convenient
- The concentrations of important cannabinoids can be very high, meaning that only a small amount is necessary to get the desired effects
- Saute vegetables
- Marinate meat
- Roast potatoes or vegetables
- Dressing for a salad
There are so many ways you can use cannabis oil. However, keep in mind the proper dosages for your recipe of choice. The general rule of thumb is to “start low and go slow” so you can find the right dose for you in your meals, drinks or other applications of choice.
Looking to get started with Medical Marijuana? At MMTCFL, we can determine if you are eligible for medical marijuana and help you get your Florida medical marijuana card. Get started with medical marijuana today by taking our online eligibility survey.