There are many potential negative health effects from using marijuana and other products containing THC during pregnancy and while breastfeeding. In fact, the U.S. Surgeon General recently advised consumers that marijuana use during pregnancy may affect fetal brain development, because THC can enter the fetal brain from the mother’s bloodstream. The Surgeon General also advised that marijuana may increase the risk of a newborn with low birth weight. Research also suggests increased risk for premature birth and potentially stillbirth 1 .
FDA recently completed an evaluation of some hemp seed-derived food ingredients and had no objections to the use of these ingredients in foods. THC and CBD are found mainly in hemp flowers, leaves, and stems, not in hemp seeds. Hemp seeds can pick up miniscule amounts of THC and CBD from contact with other plant parts, but these amounts are low enough to not raise concerns for any group, including pregnant or breastfeeding mothers.
What do we know about the effects of marijuana use during pregnancy and while breastfeeding?
FDA strongly advises against the use of cannabidiol (CBD), tetrahydrocannabinol (THC), and marijuana in any form during pregnancy or while breastfeeding.
The clinical studies that supported the approval of the one available CBD drug product identified risks related to the use of CBD, including liver toxicity (damage), extreme sleepiness, and harmful interactions with other drugs.
Cannabis is a plant of the Cannabaceae family and contains more than eighty biologically active chemical compounds. The most commonly known compounds are THC and CBD. One type of cannabis plant is marijuana, which contains varying levels of THC, the compound that produces the “high” that is often associated with marijuana. Another type of cannabis plant is hemp. Hemp plants contain extremely low amounts of THC. CBD, which does not produce a “high,” can be derived from either marijuana or hemp.
THC binds with the CB1 receptors in the brain to produce that classic weed high, while CBD has been shown to have the opposite interaction with CB1 receptors, acting as an antagonist. When consumed together, CBD appears to improve the therapeutic and enjoyable effects of THC by minimizing the unwanted side effects such as anxiety and a rapid heartbeat.
Of the emerging research into CBD’s potential medical benefits, there is concrete scientific evidence for its effectiveness in the treatment of epilepsy by reducing seizures. So much so that the United States Food and Drug Administration (FDA) approved a CBD-based drug to treat childhood epilepsy. But that’s the only hard scientific evidence on the cannabinoid.
While they may sound similar, the difference will largely dictate where you can buy these products — or if you can buy them at all.
CBD is often touted as nonpsychoactive or having no psychoactive effects, but it’s more accurately described as nonintoxicating. Why? Even though CBD won’t get you high, that subtly calm feeling you might experience after taking some CBD tincture is technically a psychoactive effect. Any substance that has a direct effect on the function of the brain is considered psychoactive. By contrast, THC can be intoxicating even at low doses.
CBD oil derived from industrial hemp plants only contains CBD, while marijuana-derived products, such as Rick Simpson Oil, have a high concentration of THC and the full range of cannabinoids found in the cannabis plant.
For those worried about THC showing up in their system, look for broad-spectrum oil or products that contain pure CBD isolate. Broad-spectrum oil, as opposed to full-spectrum oil, is refined to exclude the trace amounts of THC that may have been present in the hemp plant. Products with CBD isolate contain no THC or other plant-based cannabinoids. To find high-quality CBD, search for products that come with a certificate of analysis from a third-party testing lab to ensure that the information listed on the product label is accurate. Be careful not to confuse hemp seed oil or hemp oil, which seldom contain any CBD at all, with CBD oil. These products will provide a hearty dose of omega-3 fatty acids, but they won’t provide any potential pain-relieving or anti-anxiety effects.
It’s not just your body that influences how long it takes CBD to work, but also the quality of the CBD product and how often it’s used. Once you acquire CBD oil, the next step is to find the optimal dosing regimen, including frequency of use. The answers will depend largely on the type of product, amount of CBD inside it, and the specific ailment you are targeting. Most reputable manufacturers will provide instructions on how to properly use the product, but experimentation may be required to find the optimal dose for you and your specific needs.
Some people may be apprehensive to try CBD over concerns that it could cause them to fail a drug test. It’s highly unlikely that CBD would show up on most drug screenings, as most tests specifically look for the presence of THC and THC metabolites. But even hemp-derived CBD can contain trace amounts of THC, so there’s technically a chance — albeit extremely slim — of receiving a false-positive test result from taking an unusually large dose of CBD oil (estimates range from 1,000 to 2,000 milligrams per day).
How long does it take for CBD oil to work orally?
Consuming CBD oil via sublingual administration will deliver any effects within 30 minutes. CBD edibles have the longest onset time, and it may take two hours to feel any effects.
Bottom line: Expect to feel the effects of sublingual administration within 30 minutes. Any effects you feel should last an hour or more but be bolstered at about two hours.
Settling on the ideal CBD dosage is an important part of the treatment process, and will also impact how long CBD stays in your system. Hemp-derived CBD products are not intended to give the user a stoned buzz or intoxicated feeling, so there’s no need to be conservative with the dosage amount. Still, it’s recommended to start with a lower dosage and gradually increase it until the ideal effects are discovered.
Whether you’re smoking a high-CBD strain, puffing on a hemp flower pre-roll, or taking a draw from a CBD vape pen, inhalation is often seen as an effective method of delivery for CBD because of how quickly it’s absorbed in the body. When you smoke CBD flower or vape CBD oil, cannabinoids go directly to your lungs where they rapidly enter your bloodstream and circulate throughout your body. CBD reaches peak concentrations within three minutes after consumption, meaning the effects can be felt shortly after use.