It depends on who you ask and why they are using CBD. Isolate is best for avoiding any possible trace of THC while full-spectrum may confer the additional benefits of other cannabinoids and terpenes via the entourage effect.
CBD isolate is a crystalline solid or powder that contains 99% pure CBD. A traditional extraction process removes all the active compounds from the cannabis plant. Then, a refining process that strips away all other phytocannabinoids, including THC, and any plant matter. What remains is the CBD chemical compound in its purest form.
CBD crystalline can be measured and put into capsules or pills, allowing you to ingest an accurate dose. You can also mix CBD isolate with a variety of ingredients to create CBD-infused food and drinks. However, because CBD is not absorbed very well by the gastrointestinal tract, it has a low oral bioavailability. In order to increase bioavailability, CBD isolate can be added to carrier oils, such as MCT oil, to increase its chances of permeating the gastrointestinal system and reaching the bloodstream.
Which is better, CBD isolate or full-spectrum CBD?
It might not seem as appealing as the well-packaged CBD oil, topicals, or pre-rolls, but CBD crystalline is surprisingly versatile when it comes to consumption, and this pure powder has a number of advantages over other conventional forms of CBD.
If someone is testing for CBD isolate, yes. But common drug tests look for THC and its metabolites. And part of the point of CBD isolate is that it doesn’t contain any THC, unlike full-spectrum CBD products, which are legally permitted to contain up to 0.3% THC. Generally, worries about CBD oil and drug testing are unwarranted but it’s even less of an issue with CBD isolate.
There are various processes used to produce CBD isolate from industrial hemp extracts, such as supercritical carbon dioxide (CO2) or ethanol-based extractions. The same extraction methods can also be used as a starting point for the production of THC isolate as well, but typically with marijuana plants instead of industrial hemp. To create an isolate, a number of components are removed from the plant, including other cannabinoids, terpenes, and flavonoids, as well as fats, lipids, and other compounds. After that, the CBD compound is separated from the rest of the extraction through a series of chemical washing and separation processes.
When shopping for CBD isolate, it’s important to look for products from reputable companies that are lab-tested by a third party. This should ensure that your isolate doesn’t contain any THC, additional plant materials, or other impurities.
These elements synergize to produce a more potent result widely known as the ‘entourage effect.’ This is influenced by the theory which believes compounds in cannabis create more significant effects together than when used as isolates.
In your selection, ensure you choose only products designed for smoking/vaping – avoid smoking regular CBD oil.
The effects derived from smoking CBD isolate widely depends on some variables – notably, the product consumed and the user’s uniqueness, including body weight, medical history, etc.
CBD and Liver Function
Some prefer the joint, pipe, or vape pen methods as they are touted to offer exclusive benefits lacking with tincture and lotions.
Cytochrome P450 or CYP450 is an enzyme that helps the liver to process several drugs, including CBD. Dosing CBD with other medications that CYP450 metabolize may lead to a competition. This unhealthy competition may hinder the drugs’ metabolism, which may, in turn, cause drug accumulation in the bloodstream.
Again, generally, experts have warned against the probable dangers of smoking.
Fatigue, nausea, and several degrees of irritation are likely with extremely high doses.